Group comparison, ROI analysis and smoothing

Submitted by David on
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Discuss (controversial) issues

Hi @all,

I have a question regarding the smoothing of RS fMRI data. I want to compare patiens and controls based on ALFF, fALFF,  ReHO, VHMC and also want to use the extracted AAL ROIs to analyze each subject individually for calculating cross-correlation between ROIs. Now I was wondering if it is even necessary to apply smoothing to the data at all? I was also wondering if it is necessary to apply the head motion scrubbing regressors or if ths will corrupt the calculation of ALFF, fALL asf. ? Because as I understood scrubbing removes bad time points.

bet problem

Submitted by Ilaria_wow on

Dear Expert,

we ran into this error, I know that there is another post about it (bet error) but no one answered us: 

/usr/local/fsl/bin/bet: line 151: /bin/remove_ext: No such file or directory

...

about ReHo

Submitted by fMRInovice on
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Discuss (controversial) issues

Dear experts,

I am a novice in fMRI. I would like to ask a question about  the preprocessing of ReHo. Is it necessary to include "nuisance regression" in the preprocessing step? In some literatures it was not mentioned, while in some others it was included. Is "nuisance regression" necessary?

Thank you for your kind reply!

Charlotte.

ROI signal change

Submitted by cat on
Dear Expert, I have calculated the resting state BOLD signal for several ROI's using your valuable toolbox Dpabi in order to assess functional connectivity patterns between these ROI's. I found out that the ROI_FCMaps for each person show my 120 time points (rows) for each ROI (columns). I was surprised that some of the time point signal changes were up to negative 12 or positive 6, although most were somewhere between negative 4 and positive 4. Are these outliers? Should I be concerned about the validity of the time point data? With Kind Regards, Cat
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