同一組被試,不同天介入前後的比較應該使用Paired-t test或是Mixed Effect Analysis或是ANCOVA?

Submitted by Tony Xu on

老師您好!

想和您請教一下,

我的實驗設計是同一批人,在某一天做一特定介入的介入前以及介入之後的靜息態腦影像掃描(兩組掃描),另外一天換成另外一項不同的介入,但是一樣是做介入前以及介入之後的靜息態腦影像掃描(另外兩組)

這樣的實驗設計,希望去分析比較全腦ReHo在兩種不同介入之後的差異

(1)應該是以Paired-t test分別去比較兩天介入後減前的結果去解釋即可。另外,如果想證明不同天的介入前Baseline有無差異,則做兩天的Baseline之Paired-t test (如果這些結果均經過GRF correction,是否即可避免type I error?)

(2)或是應該做Mixed Effect Analysis 或是 ANCOVA 去分析4組數據的差異呢?

 

Extract ROI time courses

Submitted by lhenriques on

Hi,

Regarding the function 'Extract ROI time courses' and defining a random atlases as AAL, Craddock or Dosenbach, the output MATLAB file 'ROISignals' does not have the matching dimmensions according to the choosen atlas. For example: choosing the AAL atlas (116 ROIs), the dimmensions of ROISignals.mat file for one specific patient should be 80 x 116 double instead of 80 x 100 double as it results.

This does not occur with all the data, and sometimes the file's dimmensions fit the atlas' dimmensions but it seems very random when it fits and when it does not.

DPABISurf

Submitted by veeus18 on

Hello, thank you for the wonderful effort at packaging the surface and volume based processing pipelines into one package.

One quick request for the package - Please include the RSFA measure https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310892/

对于图像灰度值范围超过32767的数据,DPABI该怎么处理?

Submitted by spl1234 on

最近在用DPABI处理数据过程中发现部分数据在remove first 10 time points后出现脑区部分灰度值异常情况(全部高亮灰度值相同),怀疑是DPABI软件对输入数据的灰度范围设置有阈值,因此查看了源程序,但并没有找到,观察图像灰度值发现异常图像大量体素灰度值集中于32767处,查看说是短整型数据上限就是32767,请问这种情况该怎么处理呢?