Significance of functional correlation matrices on a group level

Submitted by David on

Hi,

I extracted the ROI time courses via DPABI and specified the AAL atlas. This gives me a of ROI correlation matrix as mat-file for every test subject. But how to determine the significance of the correlations between ROI's on a group level, i.e. if a correlation is significant over all test subjects?

YAN Chao-Gan

Tue, 09/29/2015 - 02:33

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Hi David,

For the group comparison of the correlation matrices, you can write a script by using the matlab function ttest2. Or organize them and put into SPSS.

Best,

Chao-Gan

Thanks for the answer! Just a quick question to make sure, I understood you correctly: I can test every correlation between two ROI's seperately on a group level, by using a t-test?  For example I have 50 test subjects and I have 10 ROI's and thus a 10 by 10 correlation matrix. So I do a t-test for the second entry of the matrix e.g. the correlation between ROI 1 and ROI 2 for all test subjects. I do this for every entry of the matrix (or the triangularized matrix respectively), is that correct?

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