Beijing Eyes-Open Eyes-Closed II (Beijing EOEC2) Dataset

 

Investigators and Affiliations

Chao-Gan Yan, Ph. D.1,2, Qi-Hong Zou, Ph. D.1,3, Yu-Feng Zang, Ph. D.1,4

1. State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China (When the study was performed)

2. CAS Key Laboratory of Behavioral Science, Institute of Psychology, Beijing, China (Current)

3. Center for MRI Research Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China (Current)

4. Center for Cognition and Brain Disorders, Hangzhou Normal University, Hangzhou, China (Current)

 

Acknowledgements

We would like to acknowledge the rest of the team who helped with this study, they are listed as follows:

Dong-Qiang Liu, Yong He, Chao-Zhe Zhu, Xi-Nian Zuo, Xiang-Yu Long.

 

Funding

Program for Changjiang Scholars and Innovative Research Team in University (PCSIRT)

Natural Science Foundation of China (30770594 and 30621130074)

National Key Basic Research and Development Program (973) (2003CB716101)

 

Publications Related to This Dataset

The following publications include the data shared in this data collection:

Yan, C., Liu, D., He, Y., Zou, Q., Zhu, C., Zuo, X., Long, X., Zang, Y., 2009. Spontaneous brain activity in the default mode network is sensitive to different resting-state conditions with limited cognitive load. PLoS ONE 4, e5743.

Zou, Q., Long, X., Zuo, X., Yan, C., Zhu, C., Yang, Y., Liu, D., He, Y., Zang, Y., 2009. Functional connectivity between the thalamus and visual cortex under eyes closed and eyes open conditions: A resting-state fMRI study. Hum Brain Mapp 30, 3066-3078.

 

Sample Size

Total: N = 20 (10 females, age range 10-24 years)

Inclusion criteria: No history of neurological and psychiatric disorders and never participated in any MRI experiment before.

 

Scan procedures and Parameters

MRI scanning

Briefly, the participants first underwent an EC resting-state scan session. Then, the following four sessions, three for resting-state and one for task state, were acquired and counterbalanced across the participants: 1) EC, 2) EO, 3) EO-F (Eyes open with a fixation), and 4) a fast event-related visual response task. Finally, there was a block-designed task session. Each of the six sessions lasted for eight minutes. During the three resting-state sessions, the participants were instructed to keep as motionless as possible and not to think systematically. During the EO-F session, the participants were instructed to fixate on the black crosshair in the center of a white screen. Immediately after each scanning session, the experiment operator had a short communication with the participants. All participants reported that they had not fallen asleep during the scan. The two task- related sessions (event-related and block-designed) were not analysed in the above studies.

 

Image Acquisition

MRI data were acquired using a SIEMENS TRIO 3-Tesla scanner in the Beijing Normal University Imaging Center for Brain Research. The participants lay supine with the head snugly fixed by straps and foam pads to minimize head movement. The functional images were obtained using an echo-planar imaging sequence with the following parameters: 33 axial slices, thickness/gap = 3/0.6 mm, in-plane resolution = 64 × 64, TR = 2000 ms, TE = 30 ms, flip angle = 90º, FOV = 200 × 200 mm. In addition, a T1-weighted sagittal three-dimensional magnetization-prepared rapid gradient echo (MPRAGE) sequence was acquired, covering the entire brain: 128 slices, TR = 2530 ms, TE = 3.39 ms, slice thickness = 1.33 mm, flip angle = 7º, inversion time = 1100 ms, FOV = 256 × 256 mm, and in-plane resolution = 256 × 192.

 

Phenotypic File

MRI Data