ALFF
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I am new to REST and to SPM. I would be grateful for any advice.
I have resting state fMRI data (3mins, TR 3s) and I am keen to look at the ALFF in a lesion and on the contralateral hemisphere to detect any differences. For each of my scans the lesion is in a different place, difference size, and may affect either hemisphere.
If I generate the ALFF map and calculate the mean ALFF value in lesion and in a mirror region is this valid or would higher level statistics be more appropriate?
Thanks
Krishna