关于DpabiNet的Edge-based functional connectivity问题

严老师：

您好！我用的DpabiNet做的边的功能连接分析，方法引用您前期的文章“Edge-based functional connectivity (FC) for any pair of two ROIs was computed as the Pearson's correlation coefficient of the BOLD signals, which was then transformed to z-scores using Fisher's r-to-z formula.”审稿人问了一个问题关于负功能连接的处理问题，“ Z-scores will also result in negative functional link weights, how were these further taken into account? Was the z-score normalization was calculated based on everyone’s link weight distribution separately or based on the group level weight distribution?”还恳请您指导我该怎么回答比较好呢。

期待您的回复！